Romaco Macofar’s MicroRobot 50 microdosing machine

Romaco Macofar MicroRobot 50 microdosing machine

The MicroRobot l microdosing auto is Romaco Macofar'due south innovative high-tech solution for filling cytostatic powders into vials. Three anthropomorphic robots ensure reliable processes protected past an isolator.

Germany-based Romaco is a leading international supplier of processing and packaging equipment specializing in engineering technologies for pharmaceutical solids. The group provides private machines and turnkey solutions for manufacturing and packing powders, granulates, pellets, tablets, capsules, syringes and medical devices. Romaco besides serves the nutrient and chemical industries.

Romaco operates from four European business sites, with a broad portfolio comprised of six established product brands. Noack and Siebler (Karlsruhe, Frg) supply blister, heat-sealing and rigid tube filling machines. Macofar (Bologna, Italy) markets technologies for filling sterile and non-sterile powders and liquids. Promatic (besides Bologna, Italia) specializes in cartoners, track & trace systems, and instance packers. Kilian (Cologne, Germany) offers pinch solutions for tableting while Innojet (Steinen, Deutschland) is an innovation leader for granulation and blanket.

Microdosing auto for potent and cytostatic medicines

Romaco Macofar's MicroRobot 50 is a robotic microdosing machine specially designed for filling potent and cytostatic medicines, for example, for treating cancer and automobile-allowed diseases. The technology is particularly suited for dosing sticky or hygroscopic pharmaceutical powders with irregular shapes. It tin also be used to fill sterile liquids. For loftier containment applications upwardly to level OEB five, the Macofar MicroRobot 50 tin can be supplied with isolator technology. Alternatively, it tin can exist configured with venereal or oRABS for not-cytotoxic products.

During the product procedure, three anthropomorphic robots transport the vials under an isolator to the dosing, stoppering and capping stations. Since the robots work independently of specific formats, the product modify times are significantly shorter. The servo-driven transfer system generally reduces the concentration of particles in critical areas and the risk of contamination. Due to the structured arrangement concept, the MicroRobot fifty is readily attainable and easy to make clean. The robotic grippers can be equipped with cleaning guns to validate the cleaning processes.

According to the company, the Macofar MicroRobot 50 achieves a maximum total output of 50 vials per minute, including 100 % in-procedure weight control, in other words, each vial is individually weighed both before and later on filling. If necessary, the filling volume is adjusted automatically. Numerous control systems ensure a reliable procedure and a very low waste rate with these high-priced medicines. If a stopper is missing, the filled vial is fed dorsum to the station in question, where the process is repeated, rather than removed. The same applies to missing caps. The remaining quantity of the batch has been reduced to a minimum in the dosing station, so that product loss is virtually zilch.

This ultra-compact machine is less than iv meters long and was designed with ergonomic principles in listen. All production contact parts are extremely small and lightweight. The use of components that are easy to remove and install was likewise a development priority. Access to the machine is via glove ports and RTP systems. The isolator features a congenital-in VHP generator for bio-decontamination.

The MicroRobot 50 unites the powder expertise of Romaco Macofar with Truking isolator technology. This robotic microdosing machine represents the first joint development project by the two pharmaceutical machinery specialists from Italy and China. According to the visitor, the feedback so far has been altogether positive and orders for the MicroRobot fifty accept already been received from 2 Asian pharmaceutical producers.

The MicroRobot l microdosing machine from Romaco Macofar tin be seen (via alive stream) at the Romaco S r l plant in Bologna, Italy.

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